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Physcomitrella apparently lacks any chloroplastic isoform indicating that AsA reduction in the plant exclusively occurs in cytosol (Drew et al., In order to protect against the deleterious effects of ROS, the AsA pools are required to be maintained in a reduced state

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Data Availability Statement Data from the study can be made available upon reasonable request, subject to a data sharing agreement and with appropriate ethical approval.

Yeast strains carrying a conditional mutation in Ero1 were compromised in their ability to form disulphide bonds in secreted proteins when grown at the nonpermissive temperature