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In contrast, separation techniques like high-performance liquid chromatography (HPLC) offer high selectivity and, when coupled with mass spectrometry (MS) or tandem mass spectrometry (MS/MS), provide unmatched specificity and sensitivity for comprehensive analysis of GSH metabolism [38, 39]

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At higher levels of pyridoxine, the transporters are saturated and no longer transport pyridoxine.[ref] This naturally limits the amount of vitamin B6 you can absorb at one time

To interrogate this, we utilized an AAV-TBG-Cre viral delivery system, which produces liver-specific Cre expression and subsequent genetic deletion 49,50

Two days (48 h) after the last administration, the three groups of treatment mice were sacrificed, and the stomachs were excised from the abdominal cavity