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[31] [29] [32] [33] Overall, the evidence suggests that dendritic spines are crucial for normal brain and spinal cord function

Activity-induced calcium entry triggers the activation of several distinct but sometimes converging signaling molecules, including CaMKII, protein kinase A (PKA), MAPK, or the phosphatase calcineurin pathways, each of which phosphorylates or dephosphorylate multiple transcriptional regulators within the nucleus

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NMN and NR-Cl function as NAD precursors, supporting intracellular NAD pools, while 5-Amino-1MQ is investigated for its interaction with

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