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This conclusion is strengthened first by the secondary analyses, which show the effect of metformin on vitamin B 12 deficiency, and second by replication in independent cohorts

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The pathological process can be defined as the depletion of dopamine-producing neurons located in the substantia nigra pars compacta (SNpc), a region within the midbrain (Nishioka and Hattori, 2020)

2001 Volvo Award Winner in Basic Science Studies: Effect of nutrient supply on the viability of cells from the nucleus pulposus of the intervertebral disc

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