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Furthermore, both obesity and diabetes are accompanied by significant increases in ROS and decreases in NRF2 and GPX4 levels, indicating a weakening of antioxidant capacity and activation of the ferroptosis process

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This disruption hampers the brain's capacity to effectively produce ATP through its standard metabolic processes

The study also found beta-carotene, vitamin C, and vitamin E had a stronger relationship with hearing preservation as a group than as individual nutrients

Table 6 Metabolic outcomes of alkaline water interventions in human and animal studies