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521 Additionally, personalized mRNA neoantigen vaccines, such as mRNA-4157, encode multiple antigens to stimulate a patient-specific immune response

In this section, we comprehensively summarize the pharmacological effects of molecules that regulate lactateNAMPT axis-mediated immune response and suggest previously tested drugs for tumor regression through lactateNAMPT circuit-associated metabolism in cancer as a potential modulator of antitumor immune responses (Table 2)

After SCFAs enter the liver via the portal vein, they undergo further metabolism

Therefore, when CERK is downregulated or inhibited, MMP increases and VDAC modulation occur, sensitizing NSCLC cells with oncogenic KRAS to CDDP [179]

The NAD+ metabolites increased in 40 sedentary obese men who took NR supplements (2000 mg daily) for 12 weeks
