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Strenuous exercise has resulted in increases in the inflammatory marker C-reactive protein (CRP) to levels comparable to those seen in cardiovascular disease states 12

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doi:10.1097/AUD.0000000000000729

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Concretely, VD supplementation in MASLD patients resulted in significant improvements in metabolic profiles and inflammation by upregulating levels of lipid profiles (HDL-C) and downregulating levels of liver enzymes (ALT and AST), LDL-C, and reducing pro-inflammatory microRNAs (MiR-21 and MiR-122) [81]