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However, these inhibitors are mainly small molecules that may be lack of tumor cell selectivity, and have the potential risk to deteriorate the side effects of the current anti-tumor drugs [59]

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Pickart and team have indicated that a treatment course of 100200 mgs of GHK will produce therapeutic actions in humans for wound healing applications, but that even this amount may be overstated [5]

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doi: 10.1152/ajpregu.00045.2020

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A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition

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p53 has been shown to enhances autophagy through its induction of DRAM (damage-regulated autophagy modulator), a lysosomal protein 64

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