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Moreover, the communication between MAMs and the coordination of Ca 2+ flux from the ER to mitochondria are pivotal for triggering oxidative metabolic stress, a ROS surge, and an ensuing pro-paraptotic Ca 2+ overload in breast cancer cells [153]
By lowering ferritin, glutathione may alleviate oxidative mechanisms involved in liver injury, potentially benefiting overall health by protecting against systemic inflammation and oxidative damage

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Within experimental models, it is commonly investigated for its interaction with peptide signalling networks and regulatory mechanisms

The process of ferroptosis, with its inhibitory factors and promoting factors, is illustrated in Fig
