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The PI3K/Akt pathway, which is positively induced by -catenin 118,119 , acts by phosphorylating GSK-3 to negatively regulate PPAR expression 120
[DOI] [PMC free article] [PubMed] [Google Scholar] 99.Paik J
However, CH reversed this trend, indicating that IMPs regulation of CYP1A1 and AHRR is mediated by AHR (Fig
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