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Understanding the molecular and cellular mechanisms underlying the loss or gain of disorder-related detrimental effects mediated by astrocytes in different contexts has the potential to identify new treatment strategies for a wide variety of CNS disorders

[Abstract]2023 Dec;55(1):1111-1122

[DOI] [PubMed] [Google Scholar] 178.Watanabe T., Tahara M., Todo S

These include medications such as adalimumab, infliximab, and rituximab, which are specifically designed to modulate the immune system, reducing inflammation and halting disease progression

NSCs regulate NLRP3 activation and IL-1 secretion, which are critical in the initiation of the inflammatory responses, hence preventing the release of neurotoxic pro-inflammatory factors by microglia (Chan et al., 2019)