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Influence of polyunsaturated fatty acids on Cortisol transport through MDCK and MDCK-MDR1 cells as blood-brain barrier in vitro model

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In postischemia brains, oxidative stress directs the activation of astrocytes and microglia which brings striking elevation in the inflammatory mediators such as matrix metalloproteases, chemokines, and cytokines and results in the loss of endothelial cell integrity in the brain by upregulating the neutrophil infiltration and cell adhesion molecules

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