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coelicolor strain CH999 for the expression of both type I and type II polyketides, including the full expression of the 6-deoxyerythronolide B synthase (DEBS) for production of 99

Mutations in the PI3K-Akt-mTOR pathways drive glioma survival and resistance to chemotherapy by inducing abnormal signaling [200]

and no significant difference in GFAP was found in the brains of demented and cognitively preserved people of advanced age

The difference comes down to how they work and what they target
