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Front Immunol (2022) 13:931087
The immune system hypothesis includes the alteration of the proper functioning of the central nervous system (CNS) associated with an abnormal response to common antigens, stimulation of the inflammatory and cell-mediated immune responses, and upstream regulation of oxidative and nitrosative pathways, and autoimmune responses against neuronal and other cells (Marshall-Gradisnik et al
Alcohol metabolism-mediated oxidative stress down-regulates hepcidin transcription and leads to increased duodenal iron transporter expression
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