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The histone deacetylase inhibitor valproic acid enhances acquisition, extinction, and reconsolidation of conditioned fear

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Moreover, markers of oxidative damage, including MDA, were reduced in cells that received NAC treatment

[PMID: 30585684 DOI: 10.1111/1759-7714.12938] [DOI] [PMC free article] [PubMed] [Google Scholar] 74.Volgers C, Benedikter BJ, Grauls GE, Hellebrand PHM, Savelkoul PHM, Stassen FRM

The peptide's molecular weight (340 Da in its copper-bound form) places it well below the glomerular filtration threshold of approximately 60,000 Da, meaning it passes freely through the kidneys and appears in urine within 24 hours of administration