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An initial study of depressed, unmedicated bipolar patients reported increased 5HTT binding in the thalamus, dorsal ACC, medial PFC, and insula, and decreased binding in serotoninergic brainstem nuclei raphe compared with controls (247)

Hypoglycemia Tirzepatide alone rarely causes low blood sugar, but the risk rises sharply when combined with insulin or sulfonylureas

The potential mechanisms of action are summarized in Figure 3

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Subedi AL,Q, Sharon D, Cathelin S, Xu C, Voisin V, Bader GD, et al
