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Leukocyte recruitment plays a crucial role in immune response, and defects in the trafficking of leukocytes, particularly phagocytes, could compromise immune defense and lead to organ dysfunction of the host (8, 49, 50)

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Therapeutic response to cyanocobalamin may decrease due to elderly age, infection, renal insufficiency, diabetes mellitus, marrow suppressants use (e.g

Ronneau, S., Michaux, C

IECs express several Toll-like receptors (TLRs) including TLR1, TLR2, TLR4, TLR5 and TLR9
