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Description
Toxicol Appl Pharmcol

doi: 10.1271/bbb.69.1985

The clinical manifestations of the neurocognitive impairments (if any) found by end-of-treatment neurocognitive testing, and their trajectories over time, were not evaluated in this study

As a GSTP1 inhibitor, NBDHEX binds to the H site of GSTP1, forcing GSTP1 to be released from JNK protein, thereby inducing subsequent JNK phosphorylation, leading to tumor cell cycle arrest and apoptosis [163]
The latter pathway requires a three-stage process, catalyzed by selenophosphate synthase organifying Se (probably in the form of Se 2 or H 2 Se) in an ATP-dependent process to activated selenophosphate, which phosphorylates seryl-tRNA synthetase (Figure 3)
