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Human microRNA-27a* targets Prf1 and GzmB expression to regulate NK-cell cytotoxicity
Additionally, monitoring biomarkers could guide treatment duration and dose adjustments, moving beyond one-size-fits-all protocols toward personalized therapeutic approaches optimized for individual patient characteristics and treatment goals
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SIRT1 also modifies proteins like p53 and NF-B, which affect inflammation and DNA repair pathways [10]
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