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Some research suggests that carnitine is metabolized into TMAO, which changes cholesterol metabolism and may promote plaque build-up in the arteries

doi: 10.1016/j.clnesp.2022.10.007

Moreover, hyperglycemia and hyperlipemia in rats moved water out of the cells via hyperosmolarity and, as a result, dilutional hyponatremia (lower blood sodium level) (Khattab et al

Redox proteomic analysis of brain samples demonstrated that increased OS affects the final degradative process of autophagy, which relies on the activity of the vacuolar [H + ]-ATPase (V 0 -ATPase) and cathepsin D, both oxidized in AD individuals and in DS persons at risk of developing AD (233, 298, 342, 357)

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