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By restoring the body's ability to efficiently methylate and degrade excess adrenaline, the patient experienced a near-total resolution of their hyperadrenergic POTS symptoms

By screening a number of reductants, they discovered that Tris (3-sulfonatophenyl) phosphine (TSPP) can selectively remove TNB-caps without attacking the interchain disulfides

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[DOI] [PubMed] [Google Scholar] 15.Miladinovi ., Muheim C., Bauer S., Spinnler A., Noain D., Bandarabadi M., Gallusser B., Krummenacher G., Baumann C., Adamantidis A