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While the exact trigger varies, common causes include sudden emotional or physical stress, which can trigger an autoimmune response in which the body mistakenly attacks its own melanocytes
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107 Moreover, the extremely high proliferative activity 108110 of cancer stem cells contrasts with the slow-cell-cycle of DTP cells, 105 underscoring their distinct natures
These findings suggest GPX4 expression increases in SN neurons with the development of neuromelanin and continues to increase as expression of TH is lost
