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Cynaroside similarly suppresses CXCL12, a multifunctional chemokine involved in lymphocyte/monocyte recruitment, tumor surveillance, and metastasis regulation (Libby, 2017)

MCID changes The clinical significance of reported changes in UPDRS scores should be considered with comparison to established minimal clinically important differences (MCIDs)

doi: 10.1042/bj1100020pb

PMID: 23369744
The enterocyte takes up nonheme iron across the apical membrane through the divalent metal transporter DMT1 (SLC11A2), which cotransports Fe 2+ and H + into the cell (see Chapter 5 )