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Metabolic Effects in White Adipose Tissue White Adipose Tissue (WAT) is the primary storage site for energy in the body
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In Vgat-ChR2 and Vgat-IRES-cre transgenic mice, we found for the first time that tesofensine inhibited a subset of LH GABAergic neurons, reducing their ability to promote feeding behavior, and chemogenetically silencing them enhanced tesofensines food-suppressing effects
