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Caveolin-1 scaffolding domain-derived peptide enhances erectile function by regulating oxidative stress, mitochondrial dysfunction, and apoptosis of corpus cavernosum smooth muscle cells in rats with cavernous nerve injury

M., Bibow, S

E.CohenS.RitcheyA

In plasma, the same enzyme is termed lipoprotein-associated phospholipase A 2 (Lp-PLA 2 ) and is associated with low- and high-density lipoproteins, where it acts on the outside of the phospholipid monolayer that coats the particles to hydrolyse circulating oxidized phospholipids, i.e., those with short acyl-chains, oxidized acyl-chains and F2isoprostanes esterified at the sn -2 position

The study was conducted in two parts: a 1-week, double-blind, randomized inpatient phase with daily assessments, and a 2-week open-label outpatient phase