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Similarly, prescription medications should be limited to the absolute minimum, particularly in those with cirrhosis
10.1016/j.spen.2020.100829 59 FryeR

In a landmark study by Shain et al, some important conclusions were reached

Moreover, it is not known if S-5-HT mediated the effects of L-carnitine on fatigue, as it is possible that L-carnitine could have effects unrelated to S-5-HT that could reduce fatigue and in parallel promote increased synthesis of peripheral 5-HT

