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In a study of 306 hypodiploid patients from 16 ALL cooperative groups treated between 1997 and 2013, a subgroup of 228 patients (42 who underwent HSCT) with 44 or fewer chromosomes who achieved remission were analyzed.[97][Level of evidence C2] Favorable prognostic factors included a chromosome number of 44 (compared with 43 or fewer), MRD less than 0.01% after induction, and treatment on an MRD-stratified protocol that intensified therapy for patients with higher MRD after induction

Int J Toxicol

Exocytosis of synaptic vesicles (SV) containing neurotransmitters is initiated by Ca 2+ influx through voltage-gated Ca 2+ channels during excitation of the presynaptic bouton

Three preclinical studies have examined the therapeutic potential of fisetin in PCOS, focusing on biochemical, hormonal, histological, inflammatory, and metabolic parameters (Figure 5 and Table 1)

Sun YS, Thakur K, Hu F, et al