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Researches on free radicals, more commonly referred to as reactive species, within biological systems represents one of the most dynamic fields

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A., Pinkel, D

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The glia-neuron lactate shuttle and elevated ROS promote lipid synthesis in neurons and lipid droplet accumulation in glia via APOE/D

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Sphingolipid metabolizing enzymes can modulate exosomes to direct conformational changes in A and promote the uptake of A by microglia to reduce A levels in the AD brain (Yuyama et al., 2012)

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