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2012;7(2):e30733

(2) Moderate levels of exercise-induced reactive oxygen and nitrogen species (ROS/RNS) can support training adaptations but excessive levels can result in muscle damage, inflammation, and reduced physical performance and immune function

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2.14 Statement of ethics The procedures for care and use of animals were approved by the Ethics Committee of Shanghai University of Traditional Chinese Medicine, and all applicable institutional and governmental regulations concerning the ethical use of animals were followed