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Description
Importantly, therapeutic strategies should target not only the source of initiation and/or progression of the disease but also self-amplifying mechanisms that sustain emphysema themselves, namely airspace enlargement, ECM breakdown, and progressive mechanical failure, all of which should hinder the self-perpetuation of tissue damage and stabilize lung architecture
10.1177/1947603519841675 207 PedrazzaL.Cubillos-RojasM.de MesquitaF
doi: 10.1155/2019/7860650
I., Garcia P., Buttini M., Crawford A., Glaab E., Mol
2006;290(4):L723-L729
