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Studies show improvements in working memory, processing speed, and overall mental clarity within days of treatment

Cell viability in the presence of cisplatin was also restored in A549 and U2OS cells following MKRN1 knockdown (Extended Data Fig

Hence, there is growing support for the use of compounds that target only peripheral opioid receptors, avoiding the central nervous system, which helps to reduce the risk of common opioid-related side effects

Nguyen NT, Hanieh H, Nakahama T, Kishimoto T