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BH4 treatment did increase SAM but the difference was only borderline statistically significant [ F (1, 26) = 3.03, p = 0.09
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These findings suggest that levels of AngIV in the brain potentially plays a role in the development of Alzheimers disease [1]

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Furthermore, mirtazapine administration (5 and 16 mg/kg) significantly increased the number of glia fibrillary acidic protein (GFAP)-positive astrocytes and MT-1/2- and GFAP-positive cells in the lesioned side of the striatum (Fig
