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Tryptophanase limits tryptophan availability to the host, which influences serotonin levels affecting the enteric and central nervous systems (125127)

As Sirt3 regulates mitochondrial antioxidative enzymes, a deficiency in Sirt3 can aggravate dopaminergic neuron degeneration (Outeiro et al., 2007
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Therefore, the FSP-CoQH 2 system represents an essential parallel defense mechanism that complements GPX4 activity
The brown fat-secreted adipokine neuregulin 4 is decreased in human and murine chronic kidney disease