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While the depletion of cysteine and the accumulation of cystine and Met-SO clearly indicate increased oxidative stress in SLE, none of these compounds or the unique PPP substrates R5P or S7P correlated with disease activity of untreated patients

The TLR4-NF-B pathway is also inhibited by SSB2 in LPS-induced microglia, which suppresses the activation of microglia and reduces the levels of IL-1, IL-6, and TNF-, increasing the anti-inflammatory cytokine IL-10 (Wang et al., 2023)

Prior to matrix coating, the slide was scanned on a flatbed scanner (Epson Perfection V500, Nagano, Japan)

To address these issues, researchers have developed Pt ()-based prodrugs

Townsend, 2007)