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After HT22 cytotoxicity evaluation compound 36 was found to have low cytotoxicity (CC 50 = 18.8 M) and its inhibitory activity was 16 times higher than that of OLZ (EC 50 = 0.074 M)
Peired, A
Furthermore, the vaccine for SARS-CoV-2 was found to be less effective in obese individuals compared with healthy-weight individuals (Ealey et al., 2021)
PLoS ONE 6:e20745
RASH3D19 mediates RAS activation through a positive feedback loop in KRAS-mutant cancer
