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Upon receptor binding, MT1 triggers the cAMP signaling cascade, upregulating the enzyme tyrosinase and increasing the production of eumelanin the dark, UV-protective form of melanin

Int J Cancer 129 (7): 1730-40, 2011

In a clinical cohort of 2,918 participants, fasting levels of GBB were dose-dependently associated with prevalence of CVD, coronary artery disease (CAD), and peripheral artery disease (PAD), even after adjusting for traditional risk factors

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When A09 (infectious gastroenteritis) is the primary code, diarrhea and vomiting are both integral to that diagnosis under ICD-10-CM Section I.B.5 guidelines