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This can cause damage to cells and tissues, leading to chronic inflammation. The activation of the Nrf2 pathway by sulforaphane reduces oxidative stress in a clever variety of ways, including pumping out more glutathione to neutralise free radicals, thereby reducing inflammation

A N-methylpyridinium-rich, dark roasted coffee reduced the bodyweight in pre-obese subjects, indicating a significant potential for body weight control by dark roast coffee brews containing high amounts of NMP (Kotyczka, 2011)

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