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Recent studies have shown that NOS3 can serve as a negative prognosis marker in cancer, because its expression correlates with cell invasion, metastasis, angiogenesis, and resistance to therapy [53, 54]

This phenomenon should also be studied when working with other cell types

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Song IS, Chen HH, Aiba I, Hossain A, Liang ZD, Klomp LW, et al
