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African Journal of Biomedical Research, 23(1), 7785

If these drugs are delivered to the perinuclear and intranuclear regions of tumor cells, their therapeutic effects can be maximized

Moreover, recruited neutrophils during the inductions inflammatory phase (first week) will further participate in tissue injury and fibrosis by producing matrix-degrading enzymes such as neutrophil elastase and releasing excessive ROS 12

Acute exposure of apigenin induces hepatotoxicity in Swiss mice

The evidence for this is provided by evaluating the liver function biomarkers, CYP2E1 gene expression, iron overload, oxidative stress, SIRT-1 expression and hepatic architecture damage associated with APAP overdose