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It has been shown that heme iron lead to increased endogenous formation of NOC including N-nitrosothiols, and nitrosylated heme in the gastrointestinal tract during digestion of red meat [59]
Kidney Int 1990
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SGLT-2 inhibitors and thiazolidinediones may also be used concurrently, though patients should be monitored for any unexpected interactions or adverse effects
