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In the presence of SF-1-dependent ArPII promoter, SF-1 activation led to the induction of CYP19A1 expression and subsequent activity ( 3 ( Figure 2A right part)

[DOI] [PMC free article] [PubMed] [Google Scholar] Leke, R

[DOI] [PubMed] [Google Scholar] 128.Sagoe D, McVeigh J, Bjornebekk A, Essilfie MS, Andreassen CS, Pallesen S

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In the lung, GSTT1 helps clear reactive epoxides and aldehydes from tobacco smoke and polluted air, which can otherwise damage airway cells and contribute to chronic obstructive pulmonary disease and lung cancer risk in the context of heavy exposure