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To confirm the correct hand selection and the automated building with AutoBuild , the anomalous map was inspected and confirmed anomalous signal at the regions where SeMet was built

Furthermore, AMPK regulates the activity of the glycolytic rate-limiting enzyme PFK1 by phosphorylating PFKFB3, thereby impacting key steps in glucose metabolism [93]

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Infection-induced hypoxia and inflammatory stimuli upregulate HIF-1, which then enhances immune cell metabolism and inflammatory responses, while disrupting osteoblast/osteoclast balance to aggravate bone destruction

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