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Lin JL, Huang YH, Shen YC, Huang HC, Liu PH

For analysis comparing metabolite concentrations pre- and post-zinc intervention, outliers were removed from each dataset following the ROUT method of outlier identification (Q = 1%)

Mitochondrial 3-Hydroxy-3-Methylglutaryl-CoA Synthase: a Control Enzyme in Ketogenesis

The specific mechanisms of action lie in the formation of hydrogen bonds between CGA and lipase, hydrophobic interactions between tryptophan (Trp) near the benzene ring and acyl binding bag, and weak interactions, such as van der Waals forces with surrounding amino acid residues, which together competitively inhibit the binding sites of endogenous lipase and lipoxygenase (LOX) (109)

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