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The predefined mask was used to obtain correction data in the x- and y-directions related to the previous paper 87

doi: 10.1007/s10529-007-9494-3

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The higher exposure of M4, and M5 than M0 in the terminal phase of the plasma concentration time profile suggested that intense metabolic transformation might have occurred in the intestinal lumen, where the microbial and intestinal fluid environment facilitated M0 hydrolysis

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