glutathione and vaccine Enhancing Tuberculosis Immune Responses with – Arbor Assays Immunoglobulin and cytokine changes induced

Glutathione is a vital tool in the kit for intentional living, helping you protect your cellular health so you can show up fully for the things that matter most

C., Carrillo-Ibarra S., Rivera-Valds J

Evaluation of: Glycerol production (a marker of lipolysis) 2-deoxyglucose uptake (a marker of insulin signaling) DNA synthesis (a marker of proliferation) What they found: AOD-9604 stimulated lipolysis dose-dependently from 10 M, with a plateau at 10 M Full hGH stimulated lipolysis to a similar maximum, but with different kinetics AOD-9604 did not affect glucose uptake or DNA synthesis at all, whereas hGH inhibited both (the classic lipotoxic GH effect) Fragments with different sequence (from the N-terminal part of hGH) had no lipolytic effect Why it matters: This was the first publication of AOD-9604

Pharmacol Rev 54:101127 Talebi S, Bolhassani A, Azad TM, Arashkia A, Modaresi MH (2017) Immuno-stimulating peptide derived from HMGB1 is more effective than the N-terminal domain of Gp96 as an endogenous adjuvant for improvement of protein vaccines

Abstract Germinal centres are important sites for antibody diversification and affinity maturation, and are also a common origin of B cell malignancies