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Overall, high and middlesociodemographic index (SDI) regions were associated with elevated ASIRs, whereas lowSDI regions experienced the most rapid incidence growth, potentially reflecting uneven case ascertainment and demographic variations
doi: 10.1039/D1FO03761G 31 KeY.TangD.YangQ.ZhaoH.ZhengJ.ZhuC.et al

The casualty is craving glucose which is required to shiver or exercise - both of which raise core temperature

Dermatology 57, 784790

However, factors like aging, environmental toxins, poor diet, and stress can deplete glutathione levels, leading to a variety of health challenges
