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E.KrishnakumarR.et al (2009)

There are only a few epigenetic drugs approved by the FDA, but more and more epigenetic drugs have been put into the clinical research of cancer treatment, and have achieved remarkable results

The powder has a light blue tint from the copper component

In addition, the expressions of Bax (Figure 4B), Bcl-2 (Figure 4C), and Casp3 (Figure 4D) genes, which are involved in the cell death signaling pathway (apoptosis), were measured, and the results indicated overexpressions of Bax and Casp3 genes and a downregulation of Bcl-2 in the 6-OHDA-exposed cells

The positive outcomes of clinical trials involving antioxidants to date, pave the way to investigate other antioxidants which have not come into the limelight of FRDA therapy