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Essential preparation steps include: Hand hygiene wash hands thoroughly with soap and water or use alcohol-based hand sanitiser Gather supplies B12 ampoule, sterile syringe and needle, alcohol wipes, sharps container, and cotton wool or gauze Check the medication verify the correct drug, strength, and expiry date

362 Considering the expression of the GLP-1R in thyroid C cells and the ability of GLP-1 to stimulate calcitonin secretion through a cAMP-mediated mechanism in vitro, it is plausible that calcitonin plays a role in the alterations in bone metabolism observed in GLP-1R-treated animals

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