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Resources Healthcare Common Procedural Coding System (HCPCS) Manual CMS IOM, Publication 100-04, Medicare Claims Processing Manual, Chapter 17, Section 20.1.3 and Section 70 CMS IOM, Publication 100-02, Medicare Benefit Policy Manual, Chapter 15, Section 50 CMS IOM, Publication 100-03, Medicare National Coverage Determination (NCD) Manual, Chapter 1, Part 4, Section 280.14

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In therapy, Panobinostat induces CD38 upregulation, thereby improving the anti-myeloma effects of Daratumumab ( 2.1.1.3 JAK-STAT signaling pathway The JAK-STAT pathway can influence CD38 regulation through its signaling activities

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