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Additionally, dysregulation in the phosphoinositide 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway further accentuates the demand for glutamine, driving an accelerated flux through the tricarboxylic acid (TCA) cycle to fuel the biosynthetic requirements of rapidly proliferating cancer cells [31]

The Journal of urology

Renal metabolism of amino acids: its role in interorgan amino acid exchange

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Please allow a 1-2cm deviation due to manual measurement